CBS Evening News - 1999-10-22
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Read a transcript preview of “CBS Evening News - 1999-10-22” from malgent, uploaded on 2025-10-11.
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Language: English (original, YouTube automatic captions)
[0:05] CBS Evening News
[0:08] with Dan Rather reporting from CBS News
[0:11] headquarters in New York. Good evening.
[0:14] It could be a major advance in the
[0:16] search for ways to fight, someday even
[0:18] prevent the ravages of Alzheimer's
[0:21] disease. Researchers reported today in
[0:23] the journal Science that they have
[0:25] discovered an enzyme that may trigger
[0:27] the brain destroying disease. This could
[0:30] open a whole new line of attack against
[0:32] Alzheimer's by blocking the enzyme and
[0:35] disabling the trigger. CBS's Elizabeth
[0:38] Kaledan has the facts and the prospects.
[0:42] >> For years, doctors have known that the
[0:44] brains of people with Alzheimer's
[0:46] disease gradually get clogged with
[0:48] something called amaloids. proteins that
[0:50] literally litter the brain, blocking
[0:53] neurons and erasing memories. No one
[0:56] ever knew what caused the amaloids to
[0:58] form. But today, researchers at the
[1:00] Amgen labs in California say they have
[1:03] finally figured it out.
[1:04] >> We have discovered an enzyme that plays
[1:07] a critical role in the formation of
[1:10] amaloid and this amaloid makes the
[1:13] amaloid plaques that cause Alzheimer's
[1:15] disease. Researchers believe the enzyme
[1:18] may be present in the brain long before
[1:20] any symptoms of Alzheimer's disease even
[1:22] show up. But in full-blown Alzheimer's,
[1:25] the enzyme cuts brain cell proteins and
[1:28] slices them into fragments or amaloids
[1:30] which form a toxic plaque, killing nerve
[1:33] cells in the brain. The result is that
[1:36] people like Xan White can't remember
[1:38] things, sometimes don't recognize family
[1:40] members, and gradually lose touch with
[1:42] reality. And the greatest fea